I see grape juice fulfilling the "fruit of the vine" passage, and if with modern science we can avoid people from getting intoxicated from it when taking the Lord's Supper, I say, what's the problem? i don't see grape juice over wine as a requirement, but I think it's a good change.
That's the 'anti-alcoholic' argument I referenced above, and I don't believe it's correct. I need to check with my hepatologist (liver specialist, not lizard specialist) friend to be sure, but as a medical doctor, I strongly doubt that a thimbleful of table wine in the setting of a reverent Lord's Supper would cause even the most hardened church going alcoholic to relapse, nevermind be intoxicated. The sin is not in the thing but in the heart.